Research

To help our patients find programs and treatments to address their medical conditions, our staff participates in research studies.

Dr. Martinez is a lead investigator in the following studies, specifically:

PRISM (The Pseudobulbar Affect Registry Series). Pseudobulbar Affect (PBA) is a neurologic condition that is estimated to impact over a million patients and their families in the United States. PBA occurs secondary to an otherwise unrelated neurologic disease or injury such as Alzheimer’s dementia or stroke. Symptoms of PBA include involuntary, frequent, and disruptive outbursts of crying and/or laughing. The goal of this study is to establish the prevalence and quality of life impact of PBA in patients with underlying neurologic conditions including:

  • Alzheimer’s disease
  • Amyotrophic lateral sclerosis
  • Multiple sclerosis
  • Parkinson’s disease
  • Stroke
  • Traumatic brain injury

Medtronic Implantable Systems Performance Registry (ISPR) is a database being created by Medtronic from patients who have received Medtronic implantable deep brain stimulators. The patients who obtain DBS have Parkinson’s disease, essential tremor, dystonia or Tourette syndrome. The purpose is to monitor the use and performance of Medtronic products, and to better understand what the patient needs. The data obtained will be used toward improving Medtronic’s products and developing new products and therapies in the future. They will also use the information to follow government regulations regarding product monitoring and safety. This study is ongoing and requires patient visits at least every six months.

Medtronic RECHARGE, sub-study to the ISPR, is a prospective, multi-center, open-label, non-randomized, interventional study that will assess the recharge system of the Activa RD System in subjects who are receiving DBS for Parkinson’s disease, essential tremor or dystonia (Europe only).